Description

Pyridine, 2-Bromo-4-(Difluoromethyl)-5-Fluoro- is a high-value, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is engineered to introduce specific halogenated motifs that are essential for modulating the biological activity and physicochemical properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the difluoromethyl and fluoro groups enhance lipophilicity and metabolic stability.
• Material Science Research: Employed in the synthesis of specialized ligands for catalysis or as a precursor for functionalized heterocyclic compounds used in electronic materials.
• Chemical Biology Probes: Serves as a versatile scaffold for creating molecular probes and tags used in diagnostic assays and biochemical research.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.

Basic Information

Product Name	Pyridine, 2-Bromo-4-(Difluoromethyl)-5-Fluoro-
CAS No.	1805299-88-0
Molecular Formula	C7H3BrF3N
Molecular Weight	237.01 g/mol
Synonyms	2-Bromo-4-(difluoromethyl)-5-fluoropyridine; 5-Fluoro-2-bromo-4-(difluoromethyl)pyridine; 4-(Difluoromethyl)-5-fluoro-2-bromopyridine; 2-Bromo-4-difluoromethyl-5-fluoro-pyridine; 1805299-88-0; 2-Bromo-5-fluoro-4-(difluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of Pyridine, 2-Bromo-4-(Difluoromethyl)-5-Fluoro- is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. We ensure compliance with the stringent purity requirements necessary for research and cGMP-grade synthesis. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles via HPLC, GC, NMR, and MS is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.