Description

Pyridine, 2-(Difluoromethyl)-5-Iodo- is a high-value, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both iodine and fluorine substituents, makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Key pharmaceutical intermediate for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Versatile building block in agrochemical research for developing new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Precursor for ligand synthesis in catalysis, used to create sophisticated ligands for transition metal-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Intermediate in material science for the production of specialty polymers, liquid crystals, and organic electronic materials requiring halogenated aromatic cores.
• Substrate for further functionalization via palladium-catalyzed reactions, where the iodine moiety serves as an excellent handle for cross-coupling.
• Used in academic and industrial R&D for exploring new chemical spaces and structure-activity relationships (SAR) in discovery chemistry.

Basic Information

Product Name	Pyridine, 2-(Difluoromethyl)-5-Iodo-
CAS No.	1805287-23-3
Molecular Formula	C7H4F2IN
Molecular Weight	266.92 g/mol
Synonyms	2-(Difluoromethyl)-5-iodopyridine; 5-Iodo-2-(difluoromethyl)pyridine; 2-Difluoromethyl-5-iodopyridine; 5-Iodo-2-difluoromethylpyridine; Pyridine, 2-(difluoromethyl)-5-iodo-; 1805287-23-3; 2-(Difluoromethyl)-5-iodo-pyridine
EINECS	Contact for details

Quality Control

Every batch of Pyridine, 2-(Difluoromethyl)-5-Iodo- is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical research and development processes. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.