Description

Methyl 2-Bromo-3-Chloro-6-Fluorobenzoate is a high-purity, multi-halogenated benzoate ester building block of significant importance in advanced organic synthesis. Its precise molecular architecture makes it a critical intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, especially those containing halogenated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the specific halogen pattern is crucial for bioactivity.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Can be utilized as a building block for creating molecular probes, tags, and linkers in biochemical research.
• Cross-Coupling Reactions: The bromo and chloro substituents make it a valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	Methyl 2-Bromo-3-Chloro-6-Fluorobenzoate
CAS No.	1805210-84-7
Molecular Formula	C8H5BrClFO2
Molecular Weight	267.48 g/mol
Synonyms	2-Bromo-3-chloro-6-fluorobenzoic acid methyl ester; Methyl 2-bromo-3-chloro-6-fluorobenzoate; Benzoic acid, 2-bromo-3-chloro-6-fluoro-, methyl ester; Methyl ester of 2-bromo-3-chloro-6-fluorobenzoic acid; 2-Bromo-3-chloro-6-fluoro-methylbenzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Bromo-3-Chloro-6-Fluorobenzoate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Heavy Metals	<10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.