Description

Methyl 2-Chloro-5-Fluoro-3-Methylbenzoate is a high-purity, multi-functional benzoate ester derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its precise molecular architecture, which enables the efficient construction of complex pharmacophores and agrochemical active ingredients. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to develop new active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the chloro-fluoro-methyl substitution pattern contributes to biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for the synthesis of fluorinated aromatic compounds used in electronic display technologies.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a substrate for further functional group transformations in fine chemical manufacturing.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for method development and exploring new synthetic pathways involving halogenated aromatics.

Basic Information

Product Name	Methyl 2-Chloro-5-Fluoro-3-Methylbenzoate
CAS No.	1805112-73-5
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	2-Chloro-5-fluoro-3-methylbenzoic acid methyl ester; Methyl 2-chloro-5-fluoro-m-toluate; Benzoic acid, 2-chloro-5-fluoro-3-methyl-, methyl ester; 3-Methyl-2-chloro-5-fluorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloro-5-Fluoro-3-Methylbenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.