Description

Methyl 2-(2-Aminoethoxy)Acetate Hydrochloride is a versatile organic salt and a key protected intermediate in fine chemical synthesis. Its primary value lies in providing a reactive amine group in a stable, crystalline hydrochloride form, which is crucial for controlled reactions in complex molecule assembly. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in linker chemistry for antibody-drug conjugates (ADCs) and other targeted therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific amino-ether functionalities.
• Peptide Mimetics & Linker Chemistry: Serves as a spacer or linker unit in the design of peptide analogs and bioconjugates, offering a polyethylene glycol (PEG)-like fragment with a protected amine.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for creating specialty polymers with amine-reactive sites.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating custom molecular architectures.
• Protecting Group Strategy: The methyl ester and hydrochloride salt provide orthogonal protection, useful in multi-step synthetic sequences.

Basic Information

Product Name	Methyl 2-(2-Aminoethoxy)Acetate Hydrochloride
CAS No.	1803611-80-4
Molecular Formula	C5H12ClNO3
Molecular Weight	169.61 g/mol
Synonyms	Methyl 2-(2-aminoethoxy)acetate HCl; 2-(2-Aminoethoxy)acetic acid methyl ester hydrochloride; Glycine, N-(2-hydroxyethyl)-, methyl ester, hydrochloride; Methyl (2-aminoethoxy)acetate hydrochloride; Amino-PEG2-methyl ester hydrochloride; Methyl ester of 2-(2-aminoethoxy)acetic acid hydrochloride; Methyl O-(2-aminoethyl)glycolate hydrochloride
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-(2-Aminoethoxy)Acetate Hydrochloride is produced under strict quality management protocols. Our products undergo rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent degradation and clumping.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.