Description

Ethyl 3-Bromo-4-Fluoro-2-Methylbenzoate is a high-purity, multi-functional benzoate ester derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the strategic placement of bromo and fluoro substituents on the aromatic ring, which are essential for introducing key pharmacophores and modulating electronic properties in target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex organic materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the halogenated aromatic core contributes to biological activity and environmental stability.
• Material Science Precursor: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its ability to fine-tune molecular structure and properties.
• Chemical Research & Development: Serves as a versatile substrate in cross-coupling reactions (e.g., Suzuki, Stille) and functional group transformations for exploring new synthetic pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and development candidates at various scales.

Basic Information

Product Name	Ethyl 3-Bromo-4-Fluoro-2-Methylbenzoate
CAS No.	1803604-00-3
Molecular Formula	C₁₀H₁₀BrFO₂
Molecular Weight	261.09 g/mol
Synonyms	3-Bromo-4-fluoro-2-methylbenzoic acid ethyl ester; Ethyl 3-bromo-4-fluoro-o-toluate; Benzoic acid, 3-bromo-4-fluoro-2-methyl-, ethyl ester; 2-Methyl-3-bromo-4-fluorobenzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-Bromo-4-Fluoro-2-Methylbenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain integrity and documentation traceability supports our clients' regulatory and cGMP compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.