Description

3λ-Thia-9-Azaspiro[5.5]Undecane-3,3-Dione Hydrochloride is a high-purity organic compound, specifically a spirocyclic sulfonamide derivative, that serves as a critical building block in advanced pharmaceutical research and development. Its unique molecular architecture makes it a valuable intermediate for synthesizing novel active pharmaceutical ingredients (APIs) and complex bioactive molecules. This compound is primarily utilized by research institutions and pharmaceutical companies focused on medicinal chemistry, particularly in the development of central nervous system (CNS) and metabolic disorder therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of novel drug candidates, especially for neurological targets.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the development of proprietary APIs for clinical trials.
• Biochemical Tool Compound: Employed in biochemical assays and as a probe to study specific enzyme or receptor interactions in vitro.
• Process Chemistry & Scale-Up: Used in optimizing synthetic routes from laboratory scale to pilot plant and commercial manufacturing processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical industry's outsourced R&D and production needs.

Basic Information

Product Name	3λ-Thia-9-Azaspiro[5.5]Undecane-3,3-Dione Hydrochloride
CAS No.	1803582-31-1
Molecular Formula	C9H14ClNO3S
Molecular Weight	251.73 g/mol
Synonyms	3-Thia-9-azaspiro[5.5]undecane-3,3-dione hydrochloride; 9-Azaspiro[5.5]undecane-3-thione-3,3-dioxide hydrochloride; Spiro[5.5]undecane-3-thia-9-aza-3,3-dione hydrochloride; 3λ⁶-Thia-9-azaspiro[5.5]undecane-3,3-dione hydrochloride; CAS 1803582-31-1
EINECS	Contact for details

Quality Control

Our 3λ-Thia-9-Azaspiro[5.5]Undecane-3,3-Dione Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) guidelines where applicable for pharmaceutical intermediates, and our quality commitment ensures reliable material for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.