Description

Methyl 3-Hydroxy-3-Phenylcyclobutanecarboxylate is a high-value, synthetically versatile cyclobutane derivative. This compound serves as a crucial chiral building block and synthetic intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Synthesis: Utilized as a precursor for chiral ligands, catalysts, and auxiliaries due to its rigid cyclobutane core and stereogenic center.
• Fine Chemical Production: Serves as a building block for the synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial Research: Employed in methodological studies for ring-opening, functionalization, and cross-coupling reactions of strained ring systems.
• Material Science Precursor: Potential use in the synthesis of monomers for specialized polymers with unique thermal and mechanical properties.

Basic Information

Product Name	Methyl 3-Hydroxy-3-Phenylcyclobutanecarboxylate
CAS No.	1803144-05-9
Molecular Formula	C12H14O3
Molecular Weight	206.24 g/mol
Synonyms	Methyl 3-hydroxy-3-phenylcyclobutanecarboxylate; 3-Phenyl-3-hydroxycyclobutanecarboxylic acid methyl ester; Methyl 3-phenyl-3-hydroxycyclobutanecarboxylate; 3-Hydroxy-3-phenylcyclobutanecarboxylic acid methyl ester; Cyclobutanecarboxylic acid, 3-hydroxy-3-phenyl-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Hydroxy-3-Phenylcyclobutanecarboxylate adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC or GC), chiral purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.