Description

1-(4-Pyridinyl)-1H-Pyrazol-4-Ylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its core value lies in enabling the efficient construction of complex heterocyclic systems through reliable cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a building block for creating advanced organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological pathways and protein functions.
• Academic & Contract Research: A valuable reagent for method development and exploring new synthetic routes in academic laboratories and CROs (Contract Research Organizations).
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals and advanced intermediates.

Basic Information

Product Name	1-(4-Pyridinyl)-1H-Pyrazol-4-Ylboronic Acid
CAS No.	1802481-47-5
Molecular Formula	C8H8BN3O2
Molecular Weight	189.98 g/mol
Synonyms	1-(Pyridin-4-yl)-1H-pyrazol-4-ylboronic Acid; 4-(4-Borono-1H-pyrazol-1-yl)pyridine; 1-(4-Pyridyl)-1H-pyrazole-4-boronic Acid; 1-Pyridin-4-yl-1H-pyrazole-4-boronic Acid; [1-(4-Pyridinyl)-1H-pyrazol-4-yl]boronic Acid; 1-(4-Pyridyl)-1H-pyrazol-4-ylboronic Acid; 4-(1H-Pyrazol-4-yl)pyridine-1-boronic Acid (tautomeric form); B-[1-(4-Pyridinyl)-1H-pyrazol-4-yl]boronic Acid
EINECS	Contact for details

Quality Control

Our 1-(4-Pyridinyl)-1H-Pyrazol-4-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance in sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.