Description

(4-(5-Iodo-2-Chlorobenzyl)Phenoxy)(tert-Butyl)Dimethylsilane is a specialized organosilicon compound featuring a protected phenol group, making it a valuable intermediate in advanced organic synthesis. Its core value lies in enabling the controlled introduction of complex aromatic building blocks under mild conditions, which is critical for constructing sophisticated molecular architectures. This high-purity intermediate is primarily needed by pharmaceutical and agrochemical R&D teams for the development of new active ingredients, as well as by fine chemical manufacturers producing custom molecules for electronics and materials science.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting complex small molecules.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring halogenated aromatic systems.
• Material Science Research: Serves as a precursor for creating functionalized silanes used in surface modification, adhesion promoters, and advanced polymer composites.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysis.
• Custom Synthesis and Contract Manufacturing: A critical reagent for fine chemical and CDMO (Contract Development and Manufacturing Organization) companies producing bespoke organic compounds.
• Academic and Industrial R&D: Utilized in research laboratories for methodological development in synthetic organic chemistry.

Basic Information

Product Name	(4-(5-Iodo-2-Chlorobenzyl)Phenoxy)(tert-Butyl)Dimethylsilane
CAS No.	1800112-28-0
Molecular Formula	C19H24ClIOSi
Molecular Weight	458.84 g/mol
Synonyms	tert-Butyldimethyl((4-((5-iodo-2-chlorobenzyl)oxy)phenyl)oxy)silane; 4-[(5-Iodo-2-chlorophenyl)methoxy]phenoxy-tert-butyldimethylsilane; TBDMS Ether of 4-(5-Iodo-2-chlorobenzyloxy)phenol; Silane, [4-[[(5-iodo-2-chlorophenyl)methyl]oxy]phenoxy](1,1-dimethylethyl)dimethyl-; (4-((5-Iodo-2-chlorobenzyl)oxy)phenoxy)(tert-butyl)dimethylsilane
EINECS	Contact for details

Quality Control

Our (4-(5-Iodo-2-Chlorobenzyl)Phenoxy)(tert-Butyl)Dimethylsilane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP principles where applicable to support our customers in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.