Description

Camrelizumab CAS NO 1798286-48-2 is a high-purity, humanized monoclonal antibody targeting the programmed cell death protein 1 (PD-1) receptor. This compound is a critical active pharmaceutical ingredient (API) for the development and manufacturing of advanced immunotherapies. It is primarily required by pharmaceutical companies, biotechnology research institutions, and contract development and manufacturing organizations (CDMOs) engaged in oncology drug development.

Application

• Active Pharmaceutical Ingredient (API) for the formulation of finished injectable oncology drugs.
• Key component in clinical and commercial-scale manufacturing of PD-1 inhibitor immunotherapies.
• Reference standard for analytical method development, validation, and quality control in bio-pharmaceutical labs.
• Critical raw material for biosimilar development and comparative bioactivity studies.
• Research reagent for preclinical studies investigating immune checkpoint blockade mechanisms.
• Essential material for process development and optimization in upstream and downstream bioprocessing.

Basic Information

Item	Details
Product Name	Camrelizumab
CAS No.	1798286-48-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	SHR-1210; Anti-PD-1 Monoclonal Antibody SHR-1210; Humanized Anti-PD-1 IgG4-kappa Antibody; PD-1 Inhibitor SHR-1210; Immunoglobulin G4, anti-(human programmed cell death protein 1) (human-mouse monoclonal SHR-1210 heavy chain), disulfide with human-mouse monoclonal SHR-1210 light chain, dimer
EINECS	Contact for details

Quality Control

Our Camrelizumab is manufactured under strict quality systems suitable for pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including but not limited to identity, purity, potency, and impurity profiling, to ensure it meets stringent specifications. Certificates of Analysis (COA) documenting compliance with relevant standards are provided and traceable to a reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store at the recommended temperature as per the specific grade and formulation, typically requiring controlled cold chain conditions (e.g., 2-8°C or -20°C). This product is hygroscopic (moisture-sensitive) and must be protected from humidity. For long-term stability, store under conditions defined in the stability protocol.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear to slightly opalescent solution
Identification (HPLC/MS)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 98.0% (Monomer)
Assay (Bioassay)	90.0% - 110.0% of labeled potency
Protein Content	90.0% - 110.0% of labeled claim
pH	Specification available upon request
Endotoxin	< 1.0 EU/mg
Host Cell Proteins	< 100 ppm
Sterility (for aseptic grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.