Description

4-(tert-Butyldimethylsilyloxymethyl)-5-(6-o-Triethylsilyl-1,6-Dihydroxyhexyl)-1,3-Dibenzyl-2-Imidazolidinone Benzyl Ether is a sophisticated, multi-functional organosilicon-protected intermediate of significant value in advanced organic synthesis. Its complex structure, featuring both tert-butyldimethylsilyl (TBDMS) and triethylsilyl (TES) protecting groups, makes it a critical building block for constructing complex molecular architectures with precise stereochemistry. This high-purity compound is primarily utilized by research and development teams in the pharmaceutical and fine chemical industries, where it serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, particularly those requiring specific stereocenters.
• Peptidomimetic Research: Used in the construction of imidazolidinone-based scaffolds that mimic peptide structures for drug discovery.
• Asymmetric Synthesis: Employed as a substrate or auxiliary in catalytic asymmetric reactions to induce high enantioselectivity.
• Protecting Group Strategy: The silyl ether groups provide orthogonal protection for hydroxyl functionalities during complex synthetic sequences.
• Fine Chemical Production: Serves as a specialized intermediate for manufacturing high-value agrochemicals, flavors, and fragrances.
• Academic & Industrial R&D: A valuable reagent for methodology development and exploring new chemical spaces in organic chemistry laboratories.

Basic Information

Item	Details
Product Name	4-(tert-Butyldimethylsilyloxymethyl)-5-(6-o-Triethylsilyl-1,6-Dihydroxyhexyl)-1,3-Dibenzyl-2-Imidazolidinone Benzyl Ether
CAS No.	1796929-74-2
Molecular Formula	C41H67NO5Si2
Molecular Weight	710.15 g/mol
Synonyms	1,3-Dibenzyl-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl-5-[6-[(triethylsilyl)oxy]-1,6-dihydroxyhexyl]-2-imidazolidinone benzyl ether; 4-((tert-Butyldimethylsilyloxy)methyl)-5-(6-(triethylsilyloxy)-1,6-dihydroxyhexyl)-1,3-dibenzylimidazolidin-2-one benzyl ether; TBDMS/TES Protected Imidazolidinone Intermediate; CAS 1796929-74-2; Silyl Ether Protected Chiral Imidazolidinone
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems. We employ state-of-the-art analytical techniques, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.