Description

tert-Butyl 2-Oxo-7-Azaspiro[4.5]Decane-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and lactam structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing complex molecular architectures in drug discovery programs.
• Protease Inhibitor Synthesis: Used in the synthesis pathway for compounds targeting specific protease enzymes.
• Chemical Biology Probes: Employed in the creation of specialized probes for studying enzyme function and biological pathways.
• Process Chemistry Development: Utilized for scaling up synthetic routes from laboratory to pilot plant scale.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing outsourced research and production services for the pharmaceutical industry.

Basic Information

Product Name	tert-Butyl 2-Oxo-7-Azaspiro[4.5]Decane-7-Carboxylate
CAS No.	1793108-63-0
Molecular Formula	C14H23NO3
Molecular Weight	253.34 g/mol
Synonyms	7-Boc-2-oxo-7-azaspiro[4.5]decane; tert-Butyl 2-oxo-7-azaspiro[4.5]decane-7-carboxylate; 2-Oxo-7-azaspiro[4.5]decane-7-carboxylic acid tert-butyl ester; 7-(tert-Butoxycarbonyl)-7-azaspiro[4.5]decan-2-one; 7-Boc-7-azaspiro[4.5]decan-2-one; 2-Oxo-7-azaspiro[4.5]decane-1-carboxylic acid tert-butyl ester (tautomer); Boc-7-azaspiro[4.5]decan-2-one
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Oxo-7-Azaspiro[4.5]Decane-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.