Description

tert-Butyl 2-Hydroxy-7-Azaspiro[4.5]Decane-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and azepane ring structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research. It is primarily sought by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates targeting neurological and psychiatric conditions.
• Proteolysis Targeting Chimera (PROTAC) Development: Used as a component in the linker or ligand design for novel targeted protein degradation therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying enzyme function and biological pathways.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of specialized, non-commercial compounds for client research.

Basic Information

Product Name	tert-Butyl 2-Hydroxy-7-Azaspiro[4.5]Decane-7-Carboxylate
CAS No.	1793108-62-9
Molecular Formula	C14H25NO3
Molecular Weight	255.35 g/mol
Synonyms	7-Boc-2-hydroxy-7-azaspiro[4.5]decane; tert-Butyl 2-hydroxy-7-azaspiro[4.5]decane-7-carboxylate; 2-Hydroxy-7-azaspiro[4.5]decane-7-carboxylic acid tert-butyl ester; 7-(tert-Butoxycarbonyl)-2-hydroxy-7-azaspiro[4.5]decane; 2-Hydroxy-1-oxa-8-azaspiro[4.5]decane-8-carboxylic acid tert-butyl ester (tautomeric form); Boc-2-OH-7-azaspiro[4.5]decane
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Hydroxy-7-Azaspiro[4.5]Decane-7-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.