Description

1',2'‐Dihydrospiro[Cyclopropane‐1,3'‐Indole] Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic indole scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• CNS Drug Development: Employed in the research of potential therapeutics for neurological and psychiatric disorders due to the indole moiety's relevance.
• Oncology Research: Serves as a building block for creating molecules designed to modulate specific cancer-related biological targets.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying protein function and biological mechanisms.
• Fine Chemical Synthesis: Integrated into multi-step synthetic routes for complex, high-value organic molecules in contract research and manufacturing (CRAM) settings.

Basic Information

Product Name	1',2'‐Dihydrospiro[Cyclopropane‐1,3'‐Indole] Hydrochloride
CAS No.	1788041-56-4
Molecular Formula	C10H10ClN
Molecular Weight	179.64 g/mol
Synonyms	Spiro[cyclopropane-1,3'-indole], 1',2'-dihydro-, hydrochloride; 1'H-Spiro[cyclopropane-1,3'-indole] Hydrochloride; 1',2'-Dihydrospiro[cyclopropane-1,3'-indol]-2-ium Chloride; 1',2'-Dihydro-1'H-spiro[cyclopropane-1,3'-indole] hydrochloride; Spirocyclic Indole Hydrochloride; 1'H-Spiro(cyclopropane-1,3'-indole) Hydrochloride
EINECS	Contact for details

Quality Control

Our 1',2'‐Dihydrospiro[Cyclopropane‐1,3'‐Indole] Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.