Description

Ethyl 4-Hydroxy-1-Oxa-9-Azaspiro[5.5]Undecane-9-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic heterocycle class of compounds. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within the central nervous system (CNS) and metabolic disorder research areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex target molecules for preclinical and clinical studies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying novel synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	Ethyl 4-Hydroxy-1-Oxa-9-Azaspiro[5.5]Undecane-9-Carboxylate
CAS No.	1785764-72-8
Molecular Formula	C12H19NO4
Molecular Weight	241.28 g/mol
Synonyms	9-Carbethoxy-4-hydroxy-1-oxa-9-azaspiro[5.5]undecane; Ethyl 4-hydroxy-1-oxa-9-azaspiro[5.5]undecane-9-carboxylate; 1-Oxa-9-azaspiro[5.5]undecane-9-carboxylic acid, 4-hydroxy-, ethyl ester; 1785764-72-8; 9-Azaspiro[5.5]undecane-9-carboxylic acid, 4-hydroxy-1-oxa-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Hydroxy-1-Oxa-9-Azaspiro[5.5]Undecane-9-Carboxylate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.