Description

5-Amino-2-Fluoro-4-Methoxy-Benzoic Acid Methyl Ester is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. This compound is valued for its unique molecular scaffold, which incorporates amino, fluoro, and methoxy substituents, enabling precise structural modifications. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Serves as a versatile building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Liquid Crystal & OLED Material Synthesis: Used in the research and production of advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Dye & Pigment Chemistry: Acts as an intermediate for synthesizing specialized dyes, pigments, and fluorescent markers used in analytical chemistry and imaging.
• Cross-Coupling Reactions: The amino and halogenated aromatic structure makes it suitable for palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination, Suzuki-Miyaura coupling).
• Custom Synthesis & Contract Manufacturing: Supplied to custom synthesis laboratories and CDMOs (Contract Development and Manufacturing Organizations) for client-specific research projects.

Basic Information

Product Name	5-Amino-2-Fluoro-4-Methoxy-Benzoic Acid Methyl Ester
CAS No.	1785259-87-1
Molecular Formula	C9H10FNO3
Molecular Weight	199.18 g/mol
Synonyms	Methyl 5-Amino-2-Fluoro-4-Methoxybenzoate; 2-Fluoro-4-Methoxy-5-Aminobenzoic Acid Methyl Ester; Benzoic acid, 5-amino-2-fluoro-4-methoxy-, methyl ester; 5-Amino-2-fluoro-4-methoxy methyl benzoate
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Fluoro-4-Methoxy-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.