Description

4-Morpholinecarboxylic Acid, 3-(2-Hydroxyethyl)-, 1,1-Dimethylethyl Ester is a specialized morpholine derivative that serves as a versatile building block in advanced organic synthesis. Its molecular structure, featuring both a protected carboxylic acid group and a hydroxyl functionality, makes it a valuable intermediate for constructing complex molecules with high precision. This compound is primarily utilized by research institutions and industrial R&D departments focused on developing pharmaceuticals, agrochemicals, and performance materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in constructing morpholine-based drug candidates for central nervous system and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators that require specific heterocyclic scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating chelating ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed reactions.
• Polymer Modification: Employed to introduce morpholine and hydroxyl-ester functionalities into polymer backbones, enhancing properties like solubility, adhesion, or biocompatibility for specialty coatings and resins.
• Chemical Research: A valuable reagent in academic and industrial laboratories for methodological studies in organic chemistry, including novel coupling and protection/deprotection strategies.

Basic Information

Product Name	4-Morpholinecarboxylic Acid, 3-(2-Hydroxyethyl)-, 1,1-Dimethylethyl Ester
CAS No.	1784401-31-5
Molecular Formula	C11H21NO4
Molecular Weight	231.29 g/mol
Synonyms	tert-Butyl 3-(2-hydroxyethyl)morpholine-4-carboxylate; 1,1-Dimethylethyl 3-(2-Hydroxyethyl)-4-morpholinecarboxylate; 4-Morpholinecarboxylic acid, 3-(2-hydroxyethyl)-, 1,1-dimethylethyl ester; 3-(2-Hydroxyethyl)morpholine-4-carboxylic acid tert-butyl ester; Boc-3-(2-hydroxyethyl)morpholine; N-Boc-3-(2-hydroxyethyl)morpholine
EINECS	Contact for details

Quality Control

Our production of 4-Morpholinecarboxylic Acid, 3-(2-Hydroxyethyl)-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.