Description

7-Methyl-4,7-Diazaspiro[2.5]Octane Dihydrochloride is a high-value, spirocyclic amine building block with a constrained bicyclic structure, offering unique spatial geometry for advanced molecular design. This compound is critical for medicinal chemistry research, particularly in the development of novel pharmaceuticals targeting central nervous system disorders. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce complex amine functionality into lead compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, especially for neurological targets.
• Medicinal Chemistry Research: Used as a constrained scaffold to explore structure-activity relationships (SAR) and improve metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts in asymmetric synthesis.
• Agrochemical Synthesis: Incorporated into the development of new active ingredients with enhanced biological activity.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	7-Methyl-4,7-Diazaspiro[2.5]Octane Dihydrochloride
CAS No.	1783786-17-3
Molecular Formula	C7H16Cl2N2
Molecular Weight	199.12 g/mol
Synonyms	7-Methyl-4,7-diazaspiro[2.5]octane dihydrochloride; 7-Methyl-4,7-diazaspiro[2.5]octane hydrochloride (1:2); 4,7-Diazaspiro[2.5]octane, 7-methyl-, dihydrochloride; 7-Methyl-4,7-diazaspiro[2.5]octane HCl salt; Spirocyclic amine dihydrochloride salt
EINECS	Contact for details

Quality Control

Our 7-Methyl-4,7-Diazaspiro[2.5]Octane Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.