Description

tert-Butyl 8-Amino-3-Azaspiro[5.5]Undecane-3-Carboxylate CAS NO 1782214-37-2 is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic amine structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with enhanced biological activity and pharmacokinetic properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in the areas of central nervous system (CNS) disorders and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potent and selective drug candidates targeting G-protein-coupled receptors (GPCRs).
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a versatile linker or warhead component in the design of bifunctional degraders.
• Chemical Biology Research: Used as a scaffold for creating molecular probes to study enzyme function and protein-protein interactions.
• Agrochemical Synthesis: An intermediate in the development of new-generation pesticides and herbicides with spirocyclic motifs.
• Material Science: Potential precursor for specialty polymers and ligands used in catalysis.

Basic Information

Product Name	tert-Butyl 8-Amino-3-Azaspiro[5.5]Undecane-3-Carboxylate
CAS No.	1782214-37-2
Molecular Formula	C15H28N2O2
Molecular Weight	268.40 g/mol
Synonyms	8-Amino-3-azaspiro[5.5]undecane-3-carboxylic acid tert-butyl ester; tert-Butyl 8-amino-3-azaspiro[5.5]undecane-3-carboxylate; 3-Azaspiro[5.5]undecane-8-amine, 3-(1,1-dimethylethoxy)carbonyl]-; 3-(tert-Butoxycarbonyl)-8-amino-3-azaspiro[5.5]undecane; 8-Amino-3-Boc-3-azaspiro[5.5]undecane; Boc-8-Amino-3-azaspiro[5.5]undecane; 1782214-37-2
EINECS	Contact for details

Quality Control

Our tert-Butyl 8-Amino-3-Azaspiro[5.5]Undecane-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.