Description

5-Bromo-2-Chloropyridine-4-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive halogen sites and carboxylate functionality, enabling precise molecular construction in complex chemical environments. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing complex chelating ligands and organocatalysts in asymmetric synthesis.
• Material Science Research: Employed in the creation of functionalized polymers and organic electronic materials due to its modifiable aromatic system.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	5-Bromo-2-Chloropyridine-4-Carboxylate
CAS No.	1780305-53-4
Molecular Formula	C7H3BrClNO2
Molecular Weight	236.46 g/mol
Synonyms	5-Bromo-2-chloropyridine-4-carboxylic acid; Methyl 5-bromo-2-chloropyridine-4-carboxylate (common ester form); 4-Pyridinecarboxylic acid, 5-bromo-2-chloro-; 2-Chloro-5-bromopyridine-4-carboxylic acid; 5-Bromo-2-chloroisonicotinic acid; 5-Br-2-Cl-Py-4-COOH
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Chloropyridine-4-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.