Description

5-Azaspiro[2.5]Octan-8-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic structure. This compound is of significant value in modern organic synthesis, particularly for constructing complex nitrogen-containing heterocycles essential in drug discovery. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological and metabolic disorders.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex spirocyclic and bridged heterocyclic scaffolds.
• Medicinal Chemistry: Serves as a versatile precursor for structure-activity relationship (SAR) studies and lead optimization programs.
• Fine Chemical Production: Employed in the multi-step synthesis of specialized, high-value chemicals for various industrial applications.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	5-Azaspiro[2.5]Octan-8-One Hydrochloride
CAS No.	1780166-60-0
Molecular Formula	C7H12ClNO
Molecular Weight	161.63 g/mol
Synonyms	8-Oxo-5-azaspiro[2.5]octane hydrochloride; 5-Azaspiro[2.5]octan-8-one, hydrochloride; 5-Azaspiro[2.5]octan-8-one HCl; 1-Azabicyclo[3.2.1]octan-8-one hydrochloride; 8-Oxo-1-azabicyclo[3.2.1]octane hydrochloride; 1-Azabicyclo[3.2.1]octan-8-one HCl; 5-Azaspiro[2.5]octane-8-one hydrochloride salt
EINECS	Contact for details

Quality Control

Our 5-Azaspiro[2.5]Octan-8-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.