Description

2-Pyridinecarbonitrile, 4-Bromo-3-Fluoro- is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique halogenated pyridine structure, which provides distinct reactivity for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Useful for creating labeled compounds and molecular probes for biochemical and diagnostic applications.
• Custom Synthesis & Scale-Up: A versatile starting material for contract research organizations (CROs) and custom synthesis manufacturers.

Basic Information

Product Name	2-Pyridinecarbonitrile, 4-Bromo-3-Fluoro-
CAS No.	1780027-97-5
Molecular Formula	C6H2BrFN2
Molecular Weight	200.99 g/mol
Synonyms	4-Bromo-3-fluoropicolinonitrile; 4-Bromo-3-fluoro-2-cyanopyridine; 3-Fluoro-4-bromopicolinonitrile; 2-Cyano-4-bromo-3-fluoropyridine; 4-Bromo-3-fluoropyridine-2-carbonitrile; 2-Pyridinecarbonitrile, 4-bromo-3-fluoro-; 4-Bromo-3-fluoro-2-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarbonitrile, 4-Bromo-3-Fluoro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.