Description

6-Methylspiro[Indoline-3,4'-Piperidin]-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure. This compound is of significant commercial interest for its role as a critical building block in modern medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within the fields of central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for the development of novel active pharmaceutical ingredients (APIs).
• Drug Discovery Scaffold: Used in high-throughput screening and medicinal chemistry programs to explore new chemical entities, especially for CNS targets.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses requiring a rigid, three-dimensional spirocyclic framework.
• Research & Development (R&D): Essential for academic and industrial R&D focused on heterocyclic chemistry and new molecular entities.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the cGMP production of clinical trial materials.

Basic Information

Product Name	6-Methylspiro[Indoline-3,4'-Piperidin]-2-One
CAS No.	1779850-31-5
Molecular Formula	C14H18N2O
Molecular Weight	230.31 g/mol
Synonyms	6-Methylspiro[indoline-3,4'-piperidin]-2-one; 2H-Spiro[indole-3,4'-piperidine]-2-one, 1,6-dihydro-6-methyl-; 6-Methyl-1,6-dihydro-2H-spiro[indole-3,4'-piperidine]-2-one; 6-Methyl-2H-spiro[indole-3,4'-piperidin]-2-one; 6-Methylspiro[indoline-3,4'-piperidine]-2-one; Spiro[indoline-3,4'-piperidine]-2-one, 6-methyl-; CAS 1779850-31-5
EINECS	Contact for details

Quality Control

Our 6-Methylspiro[Indoline-3,4'-Piperidin]-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications from early-stage R&D through to pre-clinical and clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.