Description

tert-Butyl 9-Amino-2-Azaspiro[5.5]Undecane-2-Carboxylate is a high-value, protected spirocyclic amine building block of significant interest in advanced organic synthesis. This compound matters because it provides a rigid, three-dimensional scaffold with orthogonal protecting groups, enabling the precise construction of complex molecular architectures. It is primarily needed by pharmaceutical and agrochemical research organizations for the development of novel active ingredients, particularly in areas targeting the central nervous system and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, especially in neurological and psychiatric therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides that require specific, three-dimensional structural motifs for target binding.
• Chemical Biology & Proteomics: Serves as a scaffold or linker in the design of chemical probes and activity-based protein profiling (ABPP) reagents.
• Peptidomimetics: The spirocyclic structure mimics peptide turn conformations, making it valuable for creating stable peptide analogs with enhanced bioavailability.
• Catalyst & Ligand Development: The amine functionality can be leveraged to create novel chiral ligands for asymmetric catalysis.
• Academic & Contract Research: Employed in academic laboratories and CROs (Contract Research Organizations) for method development and exploratory synthesis projects.

Basic Information

Product Name	tert-Butyl 9-Amino-2-Azaspiro[5.5]Undecane-2-Carboxylate
CAS No.	1779849-06-7
Molecular Formula	C15H28N2O2
Molecular Weight	268.40 g/mol
Synonyms	2-Azaspiro[5.5]undecane-2-carboxylic acid, 9-amino-, 1,1-dimethylethyl ester; 9-Amino-2-((tert-butoxy)carbonyl)-2-azaspiro[5.5]undecane; Boc-9-Amino-2-azaspiro[5.5]undecane; tert-Butyl 9-amino-2-azaspiro[5.5]undecane-2-carboxylate; 2-Azaspiro[5.5]undecane, 9-amino-, N-Boc-protected; 2-Boc-9-Amino-2-azaspiro[5.5]undecane; 1779849-06-7; Boc-protected 2-azaspiro[5.5]undecan-9-amine
EINECS	Contact for details

Quality Control

Our tert-Butyl 9-Amino-2-Azaspiro[5.5]Undecane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and cGMP-grade production for pharmaceutical applications, with documentation tailored to meet regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere (argon or nitrogen), please contact us.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.