Description

tert-Butyl 4-Amino-1-Oxa-8-Azaspiro[4.5]Decane-8-Carboxylate (Wx101856) is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is valued for its role as a critical building block in the synthesis of novel, complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D departments and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for novel drug candidates targeting neurological disorders.
• API Synthesis: Used in the construction of complex molecular architectures for potential oncology treatments.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis.
• Process Chemistry Development: Employed in route scouting and scale-up optimization for new chemical entities (NCEs).
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for client-specific synthesis projects.

Basic Information

Item	Details
Product Name	tert-Butyl 4-Amino-1-Oxa-8-Azaspiro[4.5]Decane-8-Carboxylate (Wx101856)
CAS No.	1779413-16-9
Molecular Formula	C13H24N2O3
Molecular Weight	256.34 g/mol
Synonyms	8-Boc-4-Amino-1-oxa-8-azaspiro[4.5]decane; tert-Butyl 4-amino-1-oxa-8-azaspiro[4.5]decane-8-carboxylate; 1-Oxa-8-azaspiro[4.5]decane-8-carboxylic acid, 4-amino-, 1,1-dimethylethyl ester; WX-101856; Wx101856; 1779413-16-9; Boc-protected 4-amino-1-oxa-8-azaspiro[4.5]decane
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Amino-1-Oxa-8-Azaspiro[4.5]Decane-8-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical development. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.