Description

2-(4-Methoxyphenyl)-1,3,8-Triazaspiro[4.5]Dec-1-En-4-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic triaza structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for central nervous system (CNS) and other targeted therapies. The CAS number for this compound is 1779133-27-5.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological receptors.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in API manufacturing.
• Biochemical Research: Investigated as a potential tool compound or probe for studying specific enzymatic or receptor-based pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-(4-Methoxyphenyl)-1,3,8-Triazaspiro[4.5]Dec-1-En-4-One Hydrochloride
CAS No.	1779133-27-5
Molecular Formula	C17H22N4O2 • HCl
Molecular Weight	350.85 g/mol (Free base: 314.39 g/mol)
Synonyms	1,3,8-Triazaspiro[4.5]dec-1-en-4-one, 2-(4-methoxyphenyl)-, hydrochloride; 2-(4-Methoxyphenyl)-1,3,8-triazaspiro[4.5]dec-1-en-4-one HCl; Spiro[4.5]decane-1,3,8-triaza-2-(4-methoxyphenyl)-1-en-4-one hydrochloride; CAS 1779133-27-5
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized and controlled using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for all critical parameters are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.