Description

m-Peg3-T-Butyl Ester CAS NO 1778219-81-0 is a specialized polyethylene glycol (PEG) derivative featuring a terminal tert-butyl ester group. This compound is a crucial intermediate in the synthesis of complex molecules, offering a protected carboxylic acid functionality that can be deprotected under mild acidic conditions. It is primarily sought after by researchers and manufacturers in the pharmaceutical and bioconjugation sectors for constructing drug delivery systems, antibody-drug conjugates (ADCs), and other advanced therapeutic modalities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of prodrugs and active pharmaceutical ingredients (APIs).
• Bioconjugation Linker: Used to attach therapeutic payloads (e.g., cytotoxic drugs) to targeting molecules like antibodies or peptides in ADC development.
• Polymer Modification: Serves as a functional monomer or end-capping agent for creating custom PEG-based polymers with tailored properties.
• Protecting Group Strategy: The tert-butyl ester provides a robust protective group for carboxylic acids during multi-step organic syntheses.
• Material Science Research: Employed in the development of functionalized surfaces, hydrogels, and other advanced materials.
• Diagnostic Reagent Synthesis: Used in the preparation of contrast agents or labeled compounds for imaging and diagnostics.

Basic Information

Product Name	m-Peg3-T-Butyl Ester
CAS No.	1778219-81-0
Molecular Formula	C15H30O6
Molecular Weight	306.40 g/mol
Synonyms	1-(tert-Butoxy)-3,6,9-trioxaundecan-11-oic acid; 3,6,9-Trioxaundecanedioic acid, 11-(1,1-dimethylethyl) ester; mPEG3-t-butyl ester; PEG3 tert-butyl ester; tert-Butyl-PEG3-acid; 11-(tert-Butoxy)-3,6,9-trioxaundecanoic acid; Acid-PEG3-t-butyl ester
EINECS	Contact for details

Quality Control

Our m-Peg3-T-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.