Description

tert-Butyl2-(4-Methoxyphenyl)-4-Oxo-1,3,8-Triazaspiro[4.5]Dec-1-Ene-8-Carboxylat is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic heterocycle class. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the discovery and development of new drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• API Development: Integral to the process development and scale-up of novel Active Pharmaceutical Ingredients, especially those with spirocyclic or complex heterocyclic cores.
• Contract Synthesis: Supplied to CDMOs and custom synthesis laboratories for use in client-specific research and development projects.
• Biochemical Tool Compound: Potential use in biochemical assays and as a probe for investigating biological pathways and target validation.

Basic Information

Product Name	tert-Butyl2-(4-Methoxyphenyl)-4-Oxo-1,3,8-Triazaspiro[4.5]Dec-1-Ene-8-Carboxylat
CAS No.	1774897-34-5
Molecular Formula	C19H25N3O4
Molecular Weight	359.42 g/mol
Synonyms	tert-Butyl 2-(4-methoxyphenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-1-ene-8-carboxylate; 1,3,8-Triazaspiro[4.5]dec-1-ene-8-carboxylic acid, 2-(4-methoxyphenyl)-4-oxo-, 1,1-dimethylethyl ester; 8-Boc-2-(4-methoxyphenyl)-1,3,8-triazaspiro[4.5]dec-1-en-4-one; Spiro[piperidine-4,5'-pyrrolo[1,2-c]imidazole] derivative; tert-Butyl 2-(4-methoxyphenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-1-ene-8-carboxylate; CAS 1774897-34-5
EINECS	Contact for details

Quality Control

Our tert-Butyl2-(4-Methoxyphenyl)-4-Oxo-1,3,8-Triazaspiro[4.5]Dec-1-Ene-8-Carboxylat is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The material should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.