Description

Butanedioic Acid, 2,3-Bis[[(4-Methylphenyl)Sulfonyl]Oxy]-, 1,4-Dimethyl Ester, (2R,3R)- is a high-purity, stereochemically defined chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its role as a protected chiral building block, enabling the precise construction of complex molecules with defined three-dimensional architecture. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients with specific biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new Active Pharmaceutical Ingredients (APIs), particularly in antiviral, anticancer, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific chirality is crucial for efficacy and environmental safety.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development and testing of new chiral catalysts and synthetic methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for electronics, materials science, and diagnostics.
• Academic & Institutional R&D: A critical reagent for universities and research institutes exploring novel organic transformations and natural product synthesis.

Basic Information

Item	Detail
Product Name	Butanedioic Acid, 2,3-Bis[[(4-Methylphenyl)Sulfonyl]Oxy]-, 1,4-Dimethyl Ester, (2R,3R)-
CAS No.	1773493-87-0
Molecular Formula	C22H26O10S2
Molecular Weight	514.57 g/mol
Synonyms	(2R,3R)-Dimethyl 2,3-bis[(4-methylphenyl)sulfonyloxy]succinate; (2R,3R)-2,3-Bis(p-toluenesulfonyloxy)succinic Acid Dimethyl Ester; (R,R)-Dimethyl O,O'-bis(p-toluenesulfonyl)tartrate; Dimethyl (2R,3R)-2,3-bis[(4-methylbenzenesulfonyl)oxy]butanedioate; (2R,3R)-DMTST; Chiral Ditosyl Tartrate Dimethyl Ester; Protected Tartaric Acid Derivative
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Quality is verified through comprehensive analytical techniques including HPLC for chiral purity and assay, NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) specifying identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (2R,3R)
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.