Description

2-(2-Fluorophenyl)-1,3,8-Triazaspiro[4.5]Dec-1-En-4-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic compound class. This compound is valued for its role as a critical building block in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery pipelines. It is essential for medicinal chemists and process development scientists in pharmaceutical R&D and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of investigational new drugs targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug candidates.
• CNS Drug Development: Serves as a core scaffold for compounds being explored for neurological and psychiatric disorders.
• Oncology Research: Employed in the development of potential kinase inhibitors and other targeted cancer therapies.
• Process Chemistry & Scale-Up: Used in route development and optimization for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	2-(2-Fluorophenyl)-1,3,8-Triazaspiro[4.5]Dec-1-En-4-One Hydrochloride
CAS No.	1713163-98-4
Molecular Formula	C17H20FN3O · HCl
Molecular Weight	337.82 g/mol (Free base: 301.36 g/mol)
Synonyms	2-(2-Fluorophenyl)-1,3,8-triazaspiro[4.5]dec-1-en-4-one hydrochloride; 1,3,8-Triazaspiro[4.5]dec-1-en-4-one, 2-(2-fluorophenyl)-, hydrochloride; 2-(2-Fluorophenyl)-1,3,8-triazaspiro[4.5]dec-1-en-4-one HCl; Spirocyclic Fluorophenyl Triazaone Hydrochloride; CAS 1713163-98-4
EINECS	Contact for details

Quality Control

Our 2-(2-Fluorophenyl)-1,3,8-Triazaspiro[4.5]Dec-1-En-4-One Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.