Description

3-Fluoro-2-(Piperidin-3-Yloxy)Pyridine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct molecular architecture. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and oncology therapeutics. Pharmaceutical R&D teams, contract research organizations (CROs), and fine chemical manufacturers need this building block to enable efficient and scalable synthetic routes for next-generation drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up API synthesis under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or molecular probes for biochemical and pharmacological research.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Item	Detail
Product Name	3-Fluoro-2-(Piperidin-3-Yloxy)Pyridine Hydrochloride
CAS No.	1707369-80-9
Molecular Formula	C10H14FN2O·HCl
Molecular Weight	232.69 g/mol (Free base: 196.23 g/mol)
Synonyms	3-Fluoro-2-(3-piperidinyloxy)pyridine hydrochloride; 2-(3-Piperidinyloxy)-3-fluoropyridine hydrochloride; 3-Fluoro-2-(piperidin-3-yloxy)pyridine HCl; Pyridine, 3-fluoro-2-(3-piperidinyloxy)-, hydrochloride; 1707369-80-9; 3-Fluoro-2-(3-piperidyloxy)pyridine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-(Piperidin-3-Yloxy)Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in the original sealed container to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.