Description

tert-Butyl2-(2-Methoxyphenyl)-4-Oxo-1,3,8-Triazaspiro[4.5]Dec-1-Ene-8-Carboxylat is a sophisticated spirocyclic compound featuring a triaza core, which serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis. Its unique molecular architecture makes it highly valuable for constructing complex heterocyclic frameworks essential in drug discovery and development. This compound is primarily sought by pharmaceutical R&D and fine chemical synthesis teams focused on creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a privileged scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries.
• Organic Synthesis Building Block: Used in the construction of complex spirocyclic and heterocyclic compounds due to its reactive functional groups.
• Protease Inhibitor Development: Potential application as a core structure in the design of enzyme inhibitors, given its triazaspiro[4.5]decane motif.
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying biological pathways and protein functions.
• Agrochemical Research: Exploration of its derivatives for potential use in developing new active ingredients for crop protection.

Basic Information

Product Name	tert-Butyl2-(2-Methoxyphenyl)-4-Oxo-1,3,8-Triazaspiro[4.5]Dec-1-Ene-8-Carboxylat
CAS No.	1707369-78-5
Molecular Formula	C19H25N3O4
Molecular Weight	359.42 g/mol
Synonyms	tert-Butyl 2-(2-methoxyphenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-1-ene-8-carboxylate; 8-tert-Butoxycarbonyl-2-(2-methoxyphenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-1-ene; 1,3,8-Triazaspiro[4.5]dec-1-ene-8-carboxylic acid, 2-(2-methoxyphenyl)-4-oxo-, 1,1-dimethylethyl ester; BOC-protected triazaspiro intermediate; Spirocyclic triaza building block
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management protocols, ensuring batch-to-batch consistency for critical R&D and scale-up processes. Quality is verified through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.