Description

2-Isopropyl-1,3,8-Triazaspiro[4.5]Dec-1-En-4-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic triaza compound class. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of new drug candidates, especially for central nervous system (CNS) and antiviral therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique spirocyclic scaffold.
• Process Chemistry & Scale-Up: Employed in route scouting and pilot-scale synthesis for new chemical entities (NCEs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in API manufacturing.
• Biochemical Tool Compound: Utilized in biochemical assays and as a probe for investigating specific biological pathways and targets.

Basic Information

Item	Details
Product Name	2-Isopropyl-1,3,8-Triazaspiro[4.5]Dec-1-En-4-One Hydrochloride
CAS No.	1707367-86-9
Molecular Formula	C12H21ClN4O
Molecular Weight	272.77 g/mol
Synonyms	2-Isopropyl-1,3,8-triazaspiro[4.5]dec-1-en-4-one hydrochloride; 1,3,8-Triazaspiro[4.5]dec-1-en-4-one, 2-(1-methylethyl)-, hydrochloride; 2-Isopropyl-1,3,8-triazaspiro[4.5]dec-1-en-4-one HCl; Spiro[4.5]decane-1,3,8-triaza-2-one derivative; (CAS 1707367-86-9)
EINECS	Contact for details

Quality Control

Our 2-Isopropyl-1,3,8-Triazaspiro[4.5]Dec-1-En-4-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.