Description

2-(3-Azetidinyloxy)-6-Bromopyridine Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting neurological and oncological therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization due to its azetidine and bromopyridine motifs.
• Ligand Synthesis: Employed in the development of specialized ligands for biological target modulation.
• Chemical Biology Probes: Serves as a core structure for creating probes to study enzyme function and receptor interactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Academic Research: Used in university and institutional labs for exploratory research in organic and medicinal chemistry.

Basic Information

Product Name	2-(3-Azetidinyloxy)-6-Bromopyridine Hydrochloride
CAS No.	1707367-41-6
Molecular Formula	C8H10BrClN2O
Molecular Weight	265.53 g/mol
Synonyms	6-Bromo-2-(azetidin-3-yloxy)pyridine hydrochloride; 2-(Azetidin-3-yloxy)-6-bromopyridine HCl; 6-Bromo-2-(3-azetidinyloxy)pyridine hydrochloride; 2-(3-Azetidinyloxy)-6-bromopyridine HCl; Azetidine, 3-[(6-bromo-2-pyridinyl)oxy]-, hydrochloride (1:1); 3-[(6-Bromopyridin-2-yl)oxy]azetidine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(3-Azetidinyloxy)-6-Bromopyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to GMP-grade standards and rigorous quality control ensures reliable material for your most sensitive research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.