Description

tert-Butyl 2-Methyl-4-Oxo-1,3,8-Triazaspiro[4.5]Dec-1-Ene-8-Carboxylate is a high-value, advanced pharmaceutical intermediate featuring a complex spirocyclic triaza scaffold. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within oncology and central nervous system (CNS) research.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the development of novel small-molecule drug candidates.
• Oncology Research: Used in the R&D of potential kinase inhibitors and other targeted cancer therapies.
• CNS Drug Discovery: Employed in the synthesis of compounds for neurological and psychiatric disorder research.
• Proteolysis Targeting Chimera (PROTAC) Development: Its structure is valuable for constructing linkers and warheads in bifunctional degrader molecules.
• Chemical Biology & Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and pilot-scale production of clinical trial materials.

Basic Information

Product Name	tert-Butyl 2-Methyl-4-Oxo-1,3,8-Triazaspiro[4.5]Dec-1-Ene-8-Carboxylate
CAS No.	1707365-30-7
Molecular Formula	C14H22N4O3
Molecular Weight	294.35 g/mol
Synonyms	8-Boc-2-methyl-1,3,8-triazaspiro[4.5]dec-1-en-4-one; tert-Butyl 2-methyl-4-oxo-1,3,8-triazaspiro[4.5]dec-1-ene-8-carboxylate; 1,3,8-Triazaspiro[4.5]dec-1-ene-8-carboxylic acid, 2-methyl-4-oxo-, 1,1-dimethylethyl ester; 2-Methyl-4-oxo-1,3,8-triazaspiro[4.5]dec-1-ene-8-carboxylic acid tert-butyl ester; Boc-protected spirocyclic triaza ketone; CAS 1707365-30-7
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Methyl-4-Oxo-1,3,8-Triazaspiro[4.5]Dec-1-Ene-8-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with detailed specifications to support your regulatory and R&D requirements. Our quality commitment ensures material suitable for advanced pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.