Description

3-Fluoro-2-(Pyrrolidin-3-Yloxy)Pyridine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct pyridine-pyrrolidine hybrid structure. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting the central nervous system. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged scaffold.
• Ligand Synthesis: Serves as a precursor for creating complex ligands in catalysis and biochemical assay development.
• Preclinical Development: Employed in the production of compounds for pharmacological and toxicological evaluation.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and receptor interactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	3-Fluoro-2-(Pyrrolidin-3-Yloxy)Pyridine Hydrochloride
CAS No.	1707361-72-5
Molecular Formula	C9H12ClFN2O
Molecular Weight	218.66 g/mol
Synonyms	3-Fluoro-2-[(3-pyrrolidinyl)oxy]pyridine hydrochloride; 2-[(3-Pyrrolidinyl)oxy]-3-fluoropyridine hydrochloride; 3-Fluoro-2-(3-pyrrolidinyloxy)pyridine HCl; Pyridine, 3-fluoro-2-(3-pyrrolidinyloxy)-, hydrochloride; 1707361-72-5
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-(Pyrrolidin-3-Yloxy)Pyridine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.