Description

tert-Butyl2-(3-Fluorophenyl)-4-Oxo-1,3,8-Triazaspiro[4.5]Dec-1-Ene-8-Carboxylate is a high-value, complex heterocyclic compound featuring a spirocyclic core structure, which is pivotal for its biological activity and synthetic utility. This compound serves as a key advanced intermediate in modern pharmaceutical research, particularly in the development of targeted small-molecule therapies. It is primarily sought after by pharmaceutical R&D and contract research organizations (CROs) engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other enzyme-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of lead compounds.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds to study specific biological pathways and target validation.
• Custom Synthesis: A starting material for the contract manufacturing of complex, high-purity active pharmaceutical ingredients (APIs) and reference standards.
• Preclinical Development: Supplied in development quantities for formulation studies, toxicology assessments, and early-stage clinical trial material preparation.

Basic Information

Product Name	tert-Butyl2-(3-Fluorophenyl)-4-Oxo-1,3,8-Triazaspiro[4.5]Dec-1-Ene-8-Carboxylate
CAS No.	1707361-64-5
Molecular Formula	C20H25FN4O3
Molecular Weight	388.44 g/mol
Synonyms	tert-Butyl 2-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-1-ene-8-carboxylate; 1,3,8-Triazaspiro[4.5]dec-1-ene-8-carboxylic acid, 2-(3-fluorophenyl)-4-oxo-, 1,1-dimethylethyl ester; 8-Boc-2-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-1-ene; 1707361-64-5; tert-Butyl 2-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-1-ene-8-carboxylate; Spirocyclic triazole derivative; 8-tert-Butoxycarbonyl-2-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-1-ene
EINECS	Contact for details

Quality Control

Our production of tert-Butyl2-(3-Fluorophenyl)-4-Oxo-1,3,8-Triazaspiro[4.5]Dec-1-Ene-8-Carboxylate adheres to stringent quality protocols suitable for pharmaceutical R&D. Every batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.