Description

5-Methoxy-2-(Piperidin-3-Yloxy)Pyridine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1707358-65-3. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily utilized by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel small-molecule therapies.
• API Development: Serves as a critical scaffold in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Preclinical & Clinical Trial Material: Supplied under controlled conditions for the production of materials used in non-clinical and clinical studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Chemical Reference Standard: Used as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	5-Methoxy-2-(Piperidin-3-Yloxy)Pyridine Dihydrochloride
CAS No.	1707358-65-3
Molecular Formula	C12H19Cl2N2O2
Molecular Weight	294.20 g/mol
Synonyms	5-Methoxy-2-[(3-piperidinyl)oxy]pyridine dihydrochloride; 2-(Piperidin-3-yloxy)-5-methoxypyridine dihydrochloride; 5-Methoxy-2-(3-piperidinyloxy)pyridine hydrochloride (1:2); UNII-9J8F8Y8VQN; 1707358-65-3; 5-Methoxy-2-(piperidin-3-yloxy)pyridine dihydrochloride salt
EINECS	Contact for details

Quality Control

Our 5-Methoxy-2-(Piperidin-3-Yloxy)Pyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm
Assay (Titration)	97.0% - 103.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.