Description

2-Methoxy-4-(Piperidin-4-Yloxy)Pyridine Hydrochloride is a high-purity organic salt compound with the CAS number 1707358-63-1, serving as a critical advanced pharmaceutical intermediate. Its value lies in its specific molecular architecture, which is essential for constructing complex active pharmaceutical ingredients (APIs) in modern drug discovery and development. This compound is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Chemical Research & Development: Used as a versatile synthon in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for new chemical entities (NCEs) under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Serves as a valuable reagent in university and institutional labs for exploring novel heterocyclic chemistry and reaction methodologies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials and commercial APIs.

Basic Information

Product Name	2-Methoxy-4-(Piperidin-4-Yloxy)Pyridine Hydrochloride
CAS No.	1707358-63-1
Molecular Formula	C11H16N2O2·HCl
Molecular Weight	244.72 g/mol (Free base: 208.26 g/mol)
Synonyms	4-((2-Methoxypyridin-4-yl)oxy)piperidine hydrochloride; 2-Methoxy-4-(4-piperidyloxy)pyridine hydrochloride; 4-(2-Methoxy-4-pyridyloxy)piperidine HCl; 2-Methoxy-4-(piperidin-4-yloxy)pyridine HCl; 1707358-63-1; 4-Piperidinol, 4-[(2-methoxy-4-pyridinyl)oxy]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-(Piperidin-4-Yloxy)Pyridine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure full traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.