Description

Methyl 3-(2-Chloroacetamido)-2-Hydroxypropanoate is a specialized chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its molecular structure, featuring both a chloroacetamide and a hydroxy ester moiety, makes it a versatile precursor for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily utilized by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for the synthesis of active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting specific biological pathways.
• Peptidomimetic Synthesis: Used in the construction of peptide analogs and mimetics due to its amino acid-like structure.
• Chiral Auxiliary/Reagent: Serves as a starting material for creating chiral catalysts or resolving agents in asymmetric synthesis.
• Chemical Biology Probes: Employed in the development of molecular probes and tool compounds for biochemical research.
• Agrochemical Research: Potential intermediate in the development of new, targeted crop protection agents.
• Academic & Industrial R&D: Fundamental research chemical for exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	Methyl 3-(2-Chloroacetamido)-2-Hydroxypropanoate
CAS No.	1696665-38-9
Molecular Formula	C6H10ClNO4
Molecular Weight	195.60 g/mol
Synonyms	Methyl 3-(2-chloroacetamido)-2-hydroxypropanoate; 2-Hydroxy-3-[(2-chloroacetyl)amino]propanoic acid methyl ester; Methyl 2-hydroxy-3-[(2-chloroacetyl)amino]propanoate; 3-(2-Chloroacetamido)-2-hydroxypropionic acid methyl ester; L-Serine, N-(chloroacetyl)-, methyl ester; (2R)-3-[(2-Chloroacetyl)amino]-2-hydroxypropanoic acid methyl ester (if chiral); Chloroacetamido hydroxypropanoate methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-(2-Chloroacetamido)-2-Hydroxypropanoate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and identity confirmation by spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.