Description

5-Bromo-3-Iodo-1H-Pyrrolo[2,3-C]Pyridine is a high-value, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core pyrrolopyridine scaffold, functionalized with both bromo and iodo substituents, offers versatile and orthogonal reactivity for selective cross-coupling reactions. This compound is primarily utilized by pharmaceutical and agrochemical research organizations for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active small molecules targeting the pyrrolopyridine pharmacophore.
• Agrochemical Research: Serves as a versatile scaffold for constructing novel herbicides, fungicides, and insecticides through selective functionalization.
• Material Science: Used in the development of organic semiconductors, ligands for catalysis, and other functional organic materials requiring complex halogenated heterocycles.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry due to the differential reactivity of the bromo and iodo groups.
• Cross-Coupling Reactions: An ideal substrate for Suzuki-Miyaura, Stille, and Buchwald-Hartwig amination reactions, enabling rapid diversification of molecular libraries.

Basic Information

Product Name	5-Bromo-3-Iodo-1H-Pyrrolo[2,3-C]Pyridine
CAS No.	1690341-79-7
Molecular Formula	C7H4BrIN2
Molecular Weight	322.93 g/mol
Synonyms	5-Bromo-3-iodo-1H-pyrrolo[2,3-c]pyridine; 1H-Pyrrolo[2,3-c]pyridine, 5-bromo-3-iodo-; 5-Bromo-3-iodo-7-azaindole; 3-Iodo-5-bromo-1H-pyrrolo[2,3-c]pyridine; 5-Br-3-I-7-azaindole
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Iodo-1H-Pyrrolo[2,3-C]Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.