Description

Dimethyl 2,2'-((Azanediylbis(Methylene))Bis(4,1-Phenylene))Diacetate Hydrochloride is a high-purity organic salt compound, primarily valued as a key pharmaceutical intermediate in advanced synthesis. Its molecular structure makes it a versatile building block for the development of complex active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and production in pharmaceutical, agrochemical, and specialty chemical industries where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in multi-step synthetic routes for constructing complex molecular frameworks.
• Bioconjugation & Linker Chemistry: Serves as a functionalized linker molecule in antibody-drug conjugates (ADCs) and prodrug development.
• Agrochemical Research: Employed as an intermediate in the development of new-generation herbicides and plant growth regulators.
• Material Science: A precursor for specialty polymers and advanced organic materials requiring specific amine and ester functionalities.
• Academic & Industrial R&D: Used in chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies.

Basic Information

Product Name	Dimethyl 2,2'-((Azanediylbis(Methylene))Bis(4,1-Phenylene))Diacetate Hydrochloride
CAS No.	1666113-02-5
Molecular Formula	C22H28N2O4 • HCl
Molecular Weight	428.93 g/mol (Free base: 392.47 g/mol)
Synonyms	Dimethyl 2,2'-(azanediylbis(methylene))bis(4,1-phenylene)diacetate hydrochloride; 1,4-Phenylenebis(acetic acid), 2,2'-[iminobis(methylene)]bis-, dimethyl ester, hydrochloride; Bis(4-(2-methoxy-2-oxoethyl)benzyl)amine hydrochloride; N,N-Bis[4-(2-methoxy-2-oxoethyl)benzyl]amine hydrochloride; Dimethyl 2,2'-(azanediylbis(methylene))dibenzeneacetate hydrochloride; CAS 1666113-02-5
EINECS	Contact for details

Quality Control

Our Dimethyl 2,2'-((Azanediylbis(Methylene))Bis(4,1-Phenylene))Diacetate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.