Description

Rosuvastatin Calcium Salt is a high-purity active pharmaceutical ingredient (API) and a key intermediate in the synthesis of the widely prescribed statin medication, rosuvastatin. Its primary value lies in enabling the production of effective cholesterol-lowering drugs that help manage cardiovascular disease risk. This compound is essential for pharmaceutical manufacturers and research institutions focused on developing and producing finished dosage forms, as well as for advanced chemical synthesis.

Application

• Active Pharmaceutical Ingredient (API) for the formulation of rosuvastatin-based cholesterol-lowering tablets.
• Pharmaceutical Intermediate in the final synthesis and purification steps of rosuvastatin.
• Reference Standard for quality control and analytical method development in pharmaceutical laboratories.
• Research & Development of new cardiovascular therapies and drug delivery systems.
• Generic Drug Manufacturing for producing bioequivalent versions of branded rosuvastatin medications.

Basic Information

Product Name	Rosuvastatin Calcium Salt
CAS No.	1659301-59-3
Molecular Formula	C44H54CaF2N6O12S2
Molecular Weight	1001.14 g/mol
Synonyms	Rosuvastatin Calcium; (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt; ZD4522 Calcium Salt; Crestor API; (E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[N-methyl-N-(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic Acid Calcium Salt
EINECS	Contact for details

Quality Control

Our Rosuvastatin Calcium Salt is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical use, with typical purity exceeding 99.0% by HPLC. Comprehensive testing includes identification, assay, impurity profiling, and residual solvent analysis. A Certificate of Analysis (COA) documenting all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.