Description

Cyanine7 Amine CAS NO 1650635-41-8 is a near-infrared (NIR) fluorescent dye derivative featuring a reactive primary amine group, enabling covalent conjugation to biomolecules and other substrates. This compound is critical for developing highly sensitive diagnostic assays and advanced imaging probes due to its deep tissue penetration and minimal background autofluorescence. It is essential for researchers and manufacturers in the fields of bioconjugation, in vivo imaging, flow cytometry, and pharmaceutical development who require reliable, high-purity fluorescent labels.

Application

• Bioconjugation and Probe Synthesis: Labeling of antibodies, peptides, proteins, and oligonucleotides for fluorescence-based detection.
• In Vivo Imaging: Development of NIR fluorescent probes for non-invasive deep-tissue imaging in preclinical research.
• Flow Cytometry & Microscopy: Creating fluorescent tags for cellular and subcellular analysis with minimal spectral overlap.
• Diagnostic Assay Development: Key component in lateral flow assays, ELISA, and other immunoassays requiring high sensitivity.
• Material Science: Functionalization of nanoparticles, polymers, and surfaces for sensing and imaging applications.
• Drug Delivery & Pharmacokinetics: Tracking the distribution and uptake of therapeutic agents in biological systems.

Basic Information

Product Name	Cyanine7 Amine
CAS No.	1650635-41-8
Molecular Formula	C40H47N3O2S2+ (typically as a salt, e.g., tosylate)
Molecular Weight	Contact for details (varies by counterion)
Synonyms	Cy7 amine; Sulfo-Cyanine7 amine; Cy7 NH2; 2-((1E,3E)-5-((E)-2-((1E,3E)-3-(3-aminopropyl)-5-chloro-1-(5-sulfonatopentyl)-1,3-dihydro-2H-benzo[e]indol-2-ylidene)ethylidene)-4-((E)-2-((E)-3-(3-aminopropyl)-5-chloro-1-(5-sulfonatopentyl)-1,3-dihydro-2H-benzo[e]indol-2-ylidene)ethylidene)-3-oxocyclopent-1-en-1-yl)vinyl)benzo[e]indolium; NIR dye amine; Heptamethine cyanine amine derivative
EINECS	Contact for details

Quality Control

Our Cyanine7 Amine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and functional testing for labeling efficiency. Certificates of Analysis (COA) detailing purity, absorbance/fluorescence profiles, and other critical parameters are provided to ensure traceability and compliance with your research or manufacturing standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. Allow the product to equilibrate to room temperature before opening to prevent moisture condensation. The material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Dark green to blue solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Absorption Maximum (λmax)	~747 nm ± 5 nm
Emission Maximum (λem)	~774 nm ± 5 nm
Extinction Coefficient (ε)	≥ 200,000 cm-1M-1
Solubility	Soluble in DMSO, DMF, water (sulfonated forms)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.