Description

Cyclopropene Cyanine 7 Amine is a specialized near-infrared (NIR) fluorescent dye derivative, distinguished by its reactive amine group and unique cyclopropene moiety. This compound is engineered for high-performance bio-conjugation, offering exceptional photostability and deep-tissue imaging capabilities. It is a critical reagent for researchers and manufacturers in biopharmaceutical development, in vivo imaging, and advanced diagnostic assay production.

Application

• Bio-conjugation and Probe Synthesis: Primary amine functionality enables covalent labeling of antibodies, peptides, proteins, and nanoparticles for targeted imaging.
• In Vivo Fluorescence Imaging: Cyanine 7 (Cy7) fluorophore is ideal for non-invasive deep-tissue imaging in preclinical small animal studies.
• Diagnostic Assay Development: Used as a critical fluorescent tag in lateral flow assays (LFAs), ELISA, and other immunoassay platforms.
• Flow Cytometry and Microscopy: Serves as a bright, photostable fluorescent marker for cellular and subcellular imaging applications.
• Pharmaceutical Research: Tracks drug distribution, pharmacokinetics, and target engagement in drug discovery pipelines.
• Material Science: Functionalization of polymers and surfaces for creating smart, fluorescent-responsive materials.

Basic Information

Product Name	Cyclopropene Cyanine 7 Amine
CAS No.	1650559-73-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cy7 Amine Cyclopropene; Cy7-NH2 Cyclopropene Derivative; NIR Dye Amine; Heptamethine Cyanine Amine Derivative; Fluorescent Probe Amine; Bio-conjugation Cy7 Dye; 2-((1E,3E)-5-((E)-1-(3-Aminopropyl)-3,3-dimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-1,1-dimethyl-3-(3-((1-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methylene)-2-oxocyclopropyl)indol-1-ium (IUPAC-based); CAS 1650559-73-1
EINECS	Contact for details

Quality Control

Every batch of Cyclopropene Cyanine 7 Amine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure product identity, purity, and performance consistency for your critical research and production needs. A Certificate of Analysis (COA) detailing purity (typically >95% by HPLC), identity confirmation, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Store away from strong oxidizers.

Specification

Item	Specification
Appearance	Dark green to blue solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Absorption (λmax)	~750 nm
Emission (λmax)	~773 nm
Solubility	Soluble in DMSO, DMF, methanol
Moisture Content (KF)	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.