Description

6-Bromo-5-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine (Wxfc0477) is a high-value, multi-functional heterocyclic building block featuring a bromo-substituted triazolopyridine core with a trifluoromethyl group. This compound is specifically engineered to serve as a critical intermediate in advanced pharmaceutical and agrochemical research and development. Its unique structure makes it indispensable for medicinal chemists and process development scientists working on novel active ingredients, particularly in the synthesis of kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in oncology and CNS disorders.
• Agrochemical Research: Used in the synthesis of new-generation herbicides and fungicides with enhanced activity.
• Material Science: Potential precursor for the synthesis of specialty polymers and electronic materials.
• Chemical Biology: Serves as a versatile scaffold for probe and tool compound development in biochemical assays.
• Process Chemistry: Employed in route scouting and optimization for scalable API (Active Pharmaceutical Ingredient) manufacturing.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and library production.

Basic Information

Product Name	6-Bromo-5-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine (Wxfc0477)
CAS No.	1649478-34-1
Molecular Formula	C7H3BrF3N5
Molecular Weight	294.03 g/mol
Synonyms	6-Bromo-5-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine; 2-Amino-6-bromo-5-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridine; Wxfc0477; 1649478-34-1; 6-Bromo-5-trifluoromethyl-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine; 6-Bromo-5-(trifluoromethyl)-1,2,4-triazolo[1,5-a]pyridin-2-amine
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.