Description

5-Fluoro-4-Iodopyridin-2-Amine is a high-value halogenated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both fluorine and iodine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Development: Used to create advanced herbicides, fungicides, and pesticides with improved efficacy and selectivity.
• Ligand & Catalyst Synthesis: Serves as a precursor for specialized ligands in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals.
• Chemical Biology Probes: Useful for creating labeled compounds and molecular probes for biochemical studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	5-Fluoro-4-Iodopyridin-2-Amine
CAS No.	1649470-53-0
Molecular Formula	C5H4FIN2
Molecular Weight	237.99 g/mol
Synonyms	2-Amino-5-fluoro-4-iodopyridine; 4-Iodo-5-fluoropyridin-2-amine; 5-Fluoro-4-iodo-2-pyridinamine; 5-Fluoro-4-iodopyridin-2-ylamine; 2-Pyridinamine, 5-fluoro-4-iodo-; 4-Iodo-5-fluoro-2-aminopyridine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-4-Iodopyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.