Description

Benzyl 7-(Hydroxymethyl)-5,9-Dioxa-2-Azaspiro[3.5]Nonane-2-Carboxylate is a high-value, specialized organic compound featuring a unique spirocyclic structure that combines ether, ester, and carbamate functionalities. This molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for complex organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for the construction of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Proteolysis Targeting Chimera (PROTAC) Linker: Utilized as a component in the design of PROTAC molecules due to its spirocyclic scaffold, which can confer favorable pharmacokinetic properties.
• Agrochemical Synthesis: Intermediate for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Polymer Science: Serves as a monomer or cross-linking agent for creating specialty polymers with tailored thermal and mechanical properties.
• Ligand and Catalyst Development: Used in organometallic chemistry to construct complex chelating ligands for asymmetric catalysis.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new chemical spaces in drug discovery programs.

Basic Information

Product Name	Benzyl 7-(Hydroxymethyl)-5,9-Dioxa-2-Azaspiro[3.5]Nonane-2-Carboxylate
CAS No.	1648864-66-7
Molecular Formula	C16H19NO5
Molecular Weight	305.33 g/mol
Synonyms	Benzyl 7-(hydroxymethyl)-5,9-dioxa-2-azaspiro[3.5]nonane-2-carboxylate; 5,9-Dioxa-2-azaspiro[3.5]nonane-2-carboxylic acid, 7-(hydroxymethyl)-, phenylmethyl ester; 2-Azaspiro[3.5]nonane-2-carboxylic acid, 7-(hydroxymethyl)-5,9-dioxa-, benzyl ester; Benzyl 7-hydroxymethyl-5,9-dioxa-2-azaspiro[3.5]nonane-2-carboxylate; CAS 1648864-66-7; Spirocyclic carbamate benzyl ester
EINECS	Contact for details

Quality Control

Every batch of Benzyl 7-(Hydroxymethyl)-5,9-Dioxa-2-Azaspiro[3.5]Nonane-2-Carboxylate is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are developed to meet the exacting standards required for pharmaceutical R&D and advanced synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.