Description

tert-Butyl (3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Cyclopent-3-En-1-Yl)Carbamate is a high-value, protected amine boronic ester building block designed for advanced organic synthesis. This compound matters because it provides a versatile handle for Suzuki-Miyaura cross-coupling reactions while offering orthogonal protection for the amine functionality, enabling complex, multi-step synthetic sequences. Pharmaceutical researchers and fine chemical manufacturers need it for the efficient construction of novel drug candidates, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and complex bioactive molecules.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical boronic ester coupling partner for forming carbon-carbon bonds in medicinal chemistry and material science.
• Peptidomimetic & PROTAC Synthesis: Used in the construction of peptide analogs and proteolysis-targeting chimeras (PROTACs) due to its protected amine and reactive boronate.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Precursor for creating novel bidentate ligands and organometallic catalysts.
• Polymer & Material Science: Monomer for synthesizing functional polymers and advanced organic materials with specific electronic or structural properties.

Basic Information

Product Name	tert-Butyl (3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Cyclopent-3-En-1-Yl)Carbamate
CAS No.	1643574-07-5
Molecular Formula	C16H28BNO4
Molecular Weight	309.21 g/mol
Synonyms	Boc-3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopent-3-en-1-amine; tert-Butyl N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopent-3-en-1-yl]carbamate; 1-Boc-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclopentene-1-amine; 3-(Boc-amino)-3-cyclopentene-1-boronic acid pinacol ester; (3-((tert-Butoxycarbonyl)amino)cyclopent-3-ene-1,1-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) (common misnomer); BOC-Protected 3-Aminocyclopentene Boronic Ester; 1643574-07-5
EINECS	Contact for details

Quality Control

Our tert-Butyl (3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Cyclopent-3-En-1-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Assay (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.